10/17/2024
Great news from my friend and co-investor, Peter Diamandis. One day we're going to eliminate cancer. Texas Children's Cancer and Hematology Center Stuff the Sleigh Robert F. Kennedy, Jr
What It Is: The two deadliest cancers, glioblastoma and pancreatic cancer, both achieved major breakthroughs this past week. Glioblastoma is a diagnosis you don’t want to get. It’s an aggressive brain cancer in which you are dead within 12-18 months after it’s found. University of Notre Dame researchers developed a tiny biochip that detects Epidermal Growth Factor Receptors (EGFRs)—proteins crucial in cancer growth—in just 100 microliters of blood, potentially revolutionizing early detection and improving survival odds. Pancreatic cancer, another deadly diagnosis you don’t want to receive, also has a new treatment in development. This cancer has a demoralizing 13% five-year survival rate. UMass researchers have developed a groundbreaking nanoparticle therapy combining immune-stimulating agents with tumor-targeting drugs, penetrating dense tumor barriers. In mice, 8 out of 9 showed tumor improvements, with 2 achieving complete eradication.
Why It Matters / What I Think: One of the greatest benefits of living today is the speed of medical innovation driven by exponential technologies. Early detection—such as the glioblastoma blood test—and new immune and nanoparticle therapeutics as demonstrated for pancreatic cancer are going to be developed at a faster and faster rate. Without question, the converging suite of technologies powered by AI, protein design, CRISPR, gene therapies, and new materials will be a game changer. As always, early detection is the key to effective treatment. Bottom line: this is a glimpse into a future where we conquer age-related diseases and extend our healthspan dramatically. Longevity Escape Velocity is gradually coming into view.
Live Abundantly,
Peter H. Diamandis, MD
The new blood test could be a valuable tool for identifying brain cancer at an early stage when symptoms first arise.