12/03/2020
A
PROJECT
ON
THE DESIGN AND CONSTRUCTION OF AN ELECTROPHORESIS MACHINE FOR GENOTYPE TESTING
BY
AGU, PAUL MADUABUCHI
EBSU/2014/72668
DEPARTMENT OF TECHNOLOGY AND VOCATIONAL
EDUCATION
FACULTY OF EDUCATION
EBONYI STATE UNIVERSITY
ABAKALIKI, NIGERIA
CHAPTER ONE
1. O INTRODUCTION
Electrophoresis machine is a machine used in detecting the genotype of human being which basically is AA, AS, SS.
For many years, people died of many diseases they have no knowledge of nor do they have idea of how to curve. It was not clear to them if the death was as a result of a single disease or multiple of diseases.
People worked tirelessly and laboriously but the produce from their farm was not enough to feed their family not to talk of selling them to generate a sustainable income.
Many couple witnessed sudden death of their child at birth or at their teen, without knowing the cause or how to avert it.
The advent of the knowledge of electrophoresis threw light on the genotypic constitution of cells. This gave rise to hybrid as a result of cross bred, which eventually solved the problem of low yield (harvest).
The knowledge also goes a long way to diagnose the causes of different diseases that causes death, the likes of cancer called multiple myelona, sickle cell, diseases at birth, chronic liver disease etc.
The knowledge did not only unravel the causes but also led to the development of authentic cure. Also intending couple’s eyes were opened to their genotype status, giving them room to decide on whether to go on with their marriage or not, as the likelihood or otherwise of having sickler as a child is made know to them.
1.2 BRIEF HISTORY OF ELECTROPHORESIS MACHINE
Historical fabrication of electrophoresis defined with the work of Arne Tiselius in the 1930s, and new separation processes and chemical analysis technique based on electrophoresis continued to be de