Defense Advanced Research Projects Agency - DARPA

Defense Advanced Research Projects Agency - DARPA Official page of the U.S. Defense Advanced Research Projects Agency (DARPA)

www.darpa.mil DARPA's mission is to prevent and create strategic technological surprise by maintaining the technological superiority of the U.S.
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military. The Agency sponsors revolutionary, high-payoff research bridging the gap between fundamental discoveries and their military use.

Operating as usual

Under DARPA’s SocialSim program, researchers from the University of Central Florida have developed an AI-enabled “sarcas...
05/06/2021

Under DARPA’s SocialSim program, researchers from the University of Central Florida have developed an AI-enabled “sarcasm detector” for online, textual communications. Sarcasm has been a major hurdle to increasing the accuracy of sentiment analysis, especially on social media, since sarcasm relies heavily on vocal tones, gestures, and other non-verbal communications that cannot be represented in text. Sentiment can be an important signal for online information operations to identify topics of concern or possible intent of bad actors.

The researchers have demonstrated that their deep learning model can achieve a nearly perfect sarcasm detection score on several datasets, including a major Twitter benchmark dataset. Their approach uses recurrent neural networks and attention mechanisms to track dependencies between words in a document to better classify sarcastic language. The capability is easily interpretable/explainable (a crucial differentiator from previously developed detectors), and language agnostic. https://www.darpa.mil/news-events/2021-05-06

Under DARPA’s SocialSim program, researchers from the University of Central Florida have developed an AI-enabled “sarcasm detector” for online, textual communications. Sarcasm has been a major hurdle to increasing the accuracy of sentiment analysis, especially on social media, since sarcasm relies heavily on vocal tones, gestures, and other non-verbal communications that cannot be represented in text. Sentiment can be an important signal for online information operations to identify topics of concern or possible intent of bad actors.

The researchers have demonstrated that their deep learning model can achieve a nearly perfect sarcasm detection score on several datasets, including a major Twitter benchmark dataset. Their approach uses recurrent neural networks and attention mechanisms to track dependencies between words in a document to better classify sarcastic language. The capability is easily interpretable/explainable (a crucial differentiator from previously developed detectors), and language agnostic. https://www.darpa.mil/news-events/2021-05-06

Discover DSO Day June 23-24 will detail areas of interest and related opportunities in DARPA's fundamental research offi...
05/05/2021

Discover DSO Day June 23-24 will detail areas of interest and related opportunities in DARPA's fundamental research office. DSO pursues basic S&T research to advance understanding and development of what will become future national security capabilities. https://www.darpa.mil/news-events/2021-05-04b

Discover DSO Day June 23-24 will detail areas of interest and related opportunities in DARPA's fundamental research office. DSO pursues basic S&T research to advance understanding and development of what will become future national security capabilities. https://www.darpa.mil/news-events/2021-05-04b

There is critical need to deploy portable point-of-care ultrasound to the battlefield where it could quickly and accurat...
05/04/2021

There is critical need to deploy portable point-of-care ultrasound to the battlefield where it could quickly and accurately address a broad range of injuries. DARPA’s Point-Of-Care Ultrasound Automated Interpretation (POCUS AI) program seeks to address this need by advancing artificial intelligence (AI) techniques that interpret ultrasound images for medical personnel in austere environments.

Today, DARPA announced the five research teams selected to create a prototype AI model capable of providing real-time interpretation of portable ultrasound data for multiple applications: Kitware, Inc., Netrias, Carnegie Mellon University, Novateur Research Solutions, and Drexel University. https://www.darpa.mil/news-events/2021-05-04

There is critical need to deploy portable point-of-care ultrasound to the battlefield where it could quickly and accurately address a broad range of injuries. DARPA’s Point-Of-Care Ultrasound Automated Interpretation (POCUS AI) program seeks to address this need by advancing artificial intelligence (AI) techniques that interpret ultrasound images for medical personnel in austere environments.

Today, DARPA announced the five research teams selected to create a prototype AI model capable of providing real-time interpretation of portable ultrasound data for multiple applications: Kitware, Inc., Netrias, Carnegie Mellon University, Novateur Research Solutions, and Drexel University. https://www.darpa.mil/news-events/2021-05-04

The #SubTChallenge, the most rigorous robot competition the world has seen since the 2015 DARPA Robotics Challenge, has ...
05/03/2021

The #SubTChallenge, the most rigorous robot competition the world has seen since the 2015 DARPA Robotics Challenge, has winnowed the field of contestants down to eight teams that will battle to navigate treacherous underground environments and identify real-world, mission-relevant artifacts with a chance to win a $2 million: https://www.darpa.mil/news-events/2021-05-03

The #SubTChallenge, the most rigorous robot competition the world has seen since the 2015 DARPA Robotics Challenge, has winnowed the field of contestants down to eight teams that will battle to navigate treacherous underground environments and identify real-world, mission-relevant artifacts with a chance to win a $2 million: https://www.darpa.mil/news-events/2021-05-03

Funded in part by @NIH & the DARPA Safe Genes program, research from @MassGeneral published in @NatureBiotech demonstrat...
04/30/2021

Funded in part by @NIH & the DARPA Safe Genes program, research from @MassGeneral published in @NatureBiotech demonstrates the utility of CRISPR prime editing (PE) with purified ribonucleoprotein (RNP) complexes in zebrafish and primary human cells. These prime editors had previously been delivered using DNA or mRNA vectors only, and this research offers a broader therapeutic application of this platform and additional opportunities for creation of disease models in other vertebrates. https://www.nature.com/articles/s41587-021-00901-y

Funded in part by @NIH & the DARPA Safe Genes program, research from @MassGeneral published in @NatureBiotech demonstrates the utility of CRISPR prime editing (PE) with purified ribonucleoprotein (RNP) complexes in zebrafish and primary human cells. These prime editors had previously been delivered using DNA or mRNA vectors only, and this research offers a broader therapeutic application of this platform and additional opportunities for creation of disease models in other vertebrates. https://www.nature.com/articles/s41587-021-00901-y

Partially funded by the PReemptive Expression of Protective Alleles and Response Elements (PREPARE) program, researchers...
04/29/2021

Partially funded by the PReemptive Expression of Protective Alleles and Response Elements (PREPARE) program, researchers at @broadinstitute and colleagues have developed tissue atlases from autopsies conducted on deceased COVID patients. Pathology and cellular targets were published today in @Nature, and offer key insights into the biological impact of severe diseases and possible treatments. https://www.nature.com/articles/s41586-021-03570-8

Partially funded by the PReemptive Expression of Protective Alleles and Response Elements (PREPARE) program, researchers at @broadinstitute and colleagues have developed tissue atlases from autopsies conducted on deceased COVID patients. Pathology and cellular targets were published today in @Nature, and offer key insights into the biological impact of severe diseases and possible treatments. https://www.nature.com/articles/s41586-021-03570-8

In the 43rd episode of the Voices from DARPA podcast, Scott Wierzbanowski, a program manager since 2016 in the agency’s ...
04/26/2021

In the 43rd episode of the Voices from DARPA podcast, Scott Wierzbanowski, a program manager since 2016 in the agency’s Tactical Technology Office, recounts how he came of age in a family of test pilots and then embraced the mission of fostering technologies for amplifying the capabilities of airmen, their aircraft, and other defense assets in the sky. In this podcast, titled the “Sky Master,” Scott explains how the sky hasn’t even been the limit during his time at DARPA. https://www.darpa.mil/about-us/podcast

In the 43rd episode of the Voices from DARPA podcast, Scott Wierzbanowski, a program manager since 2016 in the agency’s Tactical Technology Office, recounts how he came of age in a family of test pilots and then embraced the mission of fostering technologies for amplifying the capabilities of airmen, their aircraft, and other defense assets in the sky. In this podcast, titled the “Sky Master,” Scott explains how the sky hasn’t even been the limit during his time at DARPA. https://www.darpa.mil/about-us/podcast

The software vulnerability disclosure process is fraught with challenges that put cybersecurity researchers and software...
04/23/2021

The software vulnerability disclosure process is fraught with challenges that put cybersecurity researchers and software makers at odds. DARPA’s SIEVE program is exploring potential solutions to this problem through the use of zero-knowledge proofs (ZKPs). One year into SIEVE, two research teams led by Galois and Trail of Bits have demonstrated that these mathematically verifiable problem statements could potentially be used by a vulnerability researcher (the prover) to convince a software maker (the verifier) that they possess information about a bug or exploit without revealing sensitive details – like how the vulnerability was uncovered.
#cybersecurity #software #zeroknowledge

The software vulnerability disclosure process is fraught with challenges that put cybersecurity researchers and software makers at odds. DARPA’s SIEVE program is exploring potential solutions to this problem through the use of zero-knowledge proofs (ZKPs). One year into SIEVE, two research teams led by Galois and Trail of Bits have demonstrated that these mathematically verifiable problem statements could potentially be used by a vulnerability researcher (the prover) to convince a software maker (the verifier) that they possess information about a bug or exploit without revealing sensitive details – like how the vulnerability was uncovered.
#cybersecurity #software #zeroknowledge

DYK DARPA offers Small Business Innovation Research (SBIR) & Small Business Technology Transfer (STTR) grants? These pro...
04/20/2021

DYK DARPA offers Small Business Innovation Research (SBIR) & Small Business Technology Transfer (STTR) grants? These programs are highly competitive, and encourage domestic small businesses to engage in Federal Research/Research and Development (R/R&D) with the potential for commercialization.

One recent recipient, SecondWave Systems, is conducting first-in human clinical trials using ultrasound stimulation to address hyperinflammation in severe cases of COVID-19. Learn more at how to work with us at: https://www.darpa.mil/work-with-us/for-small-businesses/participate-sbir-sttr-program

DYK DARPA offers Small Business Innovation Research (SBIR) & Small Business Technology Transfer (STTR) grants? These programs are highly competitive, and encourage domestic small businesses to engage in Federal Research/Research and Development (R/R&D) with the potential for commercialization.

One recent recipient, SecondWave Systems, is conducting first-in human clinical trials using ultrasound stimulation to address hyperinflammation in severe cases of COVID-19. Learn more at how to work with us at: https://www.darpa.mil/work-with-us/for-small-businesses/participate-sbir-sttr-program

Chemical and biological (CB) threats have become increasingly ubiquitous and diverse, presenting significant risks to wa...
04/19/2021

Chemical and biological (CB) threats have become increasingly ubiquitous and diverse, presenting significant risks to warfighters in theater and stability operators during pandemic outbreaks. State-of-the-art personal protective equipment (PPE) can be bulky, heavy, and cumbersome, often severely limiting user mobility and performance. The Personalized Protective Biosystem (PPB) program aims to develop technology that reduces the need for burdensome protective equipment while increasing individual protection against CB threats.

DARPA recently awarded contracts to the following performers, FLIR Systems, Leidos, and Charles River Analytics, to develop lightweight materials and adaptable, tissue-protective countermeasures to provide on-demand, broad spectrum, and rapid long-term protection. Performers will seek to leverage molecular technologies and commensal organisms to unburden protective equipment demands from the user.
https://www.darpa.mil/news-events/2021-04-19

Chemical and biological (CB) threats have become increasingly ubiquitous and diverse, presenting significant risks to warfighters in theater and stability operators during pandemic outbreaks. State-of-the-art personal protective equipment (PPE) can be bulky, heavy, and cumbersome, often severely limiting user mobility and performance. The Personalized Protective Biosystem (PPB) program aims to develop technology that reduces the need for burdensome protective equipment while increasing individual protection against CB threats.

DARPA recently awarded contracts to the following performers, FLIR Systems, Leidos, and Charles River Analytics, to develop lightweight materials and adaptable, tissue-protective countermeasures to provide on-demand, broad spectrum, and rapid long-term protection. Performers will seek to leverage molecular technologies and commensal organisms to unburden protective equipment demands from the user.
https://www.darpa.mil/news-events/2021-04-19

As part of the DARPA INTERfering and Co-Evolving Prevention and Therapy (INTERCEPT) program, Institut Pasteur researcher...
04/18/2021

As part of the DARPA INTERfering and Co-Evolving Prevention and Therapy (INTERCEPT) program, Institut Pasteur researchers and colleagues have recently identified defective viral genome sequences that can be used as therapeutic interfering particles against Zika virus infection and show antiviral activity in mosquitoes and mice. The program aims to harness viral evolution to create a novel, adaptive form of medical countermeasure—therapeutic interfering particles (TIPs)—that outcompetes viruses in the body to prevent or treat infection. Learn more in Nature Communication: https://www.nature.com/articles/s41467-021-22341-7]

As part of the DARPA INTERfering and Co-Evolving Prevention and Therapy (INTERCEPT) program, Institut Pasteur researchers and colleagues have recently identified defective viral genome sequences that can be used as therapeutic interfering particles against Zika virus infection and show antiviral activity in mosquitoes and mice. The program aims to harness viral evolution to create a novel, adaptive form of medical countermeasure—therapeutic interfering particles (TIPs)—that outcompetes viruses in the body to prevent or treat infection. Learn more in Nature Communication: https://www.nature.com/articles/s41467-021-22341-7]

As part of the DARPA Living Foundries program, researchers at North Dakota State University and Zymergen successfully de...
04/18/2021

As part of the DARPA Living Foundries program, researchers at North Dakota State University and Zymergen successfully demonstrated their high-throughput approach to carry out polyesterification reactions. Published in the Journal of Polymer Science, their method offers highly controllable and reproducible reaction conditions in every reactor coupled with the ability to use a minimum amount of reagents.

DARPA’s Living Foundries program aims to enable adaptable, scalable, and on-demand production of such molecules by programming the fundamental metabolic processes of biological systems to generate a vast number of complex molecules that are not otherwise accessible: https://onlinelibrary.wiley.com/doi/10.1002/pol.20210059

As part of the DARPA Living Foundries program, researchers at North Dakota State University and Zymergen successfully demonstrated their high-throughput approach to carry out polyesterification reactions. Published in the Journal of Polymer Science, their method offers highly controllable and reproducible reaction conditions in every reactor coupled with the ability to use a minimum amount of reagents.

DARPA’s Living Foundries program aims to enable adaptable, scalable, and on-demand production of such molecules by programming the fundamental metabolic processes of biological systems to generate a vast number of complex molecules that are not otherwise accessible: https://onlinelibrary.wiley.com/doi/10.1002/pol.20210059

Had COVID and think you don’t need a vaccine? Think again. Data published in Lancet Respiratory Medicine by ECHO perform...
04/16/2021

Had COVID and think you don’t need a vaccine? Think again. Data published in Lancet Respiratory Medicine by ECHO performers at the Icahn School of Medicine at Mount Sinai and colleagues demonstrate that past COVID-19 infection doesn’t fully protect young people against reinfection.

The study found that participants who had not previously been infected with SARS-CoV-2 (seronegative) had a five times greater risk of infection than participants who were previously infected (seropositive), but seropositive people are still at risk of reinfection.
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00158-2/fulltext

Had COVID and think you don’t need a vaccine? Think again. Data published in Lancet Respiratory Medicine by ECHO performers at the Icahn School of Medicine at Mount Sinai and colleagues demonstrate that past COVID-19 infection doesn’t fully protect young people against reinfection.

The study found that participants who had not previously been infected with SARS-CoV-2 (seronegative) had a five times greater risk of infection than participants who were previously infected (seropositive), but seropositive people are still at risk of reinfection.
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00158-2/fulltext

A Proposers Day for our recently announced Quantum Benchmarking program is scheduled for April 20 via webcast. Potential...
04/13/2021

A Proposers Day for our recently announced Quantum Benchmarking program is scheduled for April 20 via webcast. Potential proposers may find more information and registration details here: https://go.usa.gov/xHgtg

A Proposers Day for our recently announced Quantum Benchmarking program is scheduled for April 20 via webcast. Potential proposers may find more information and registration details here: https://go.usa.gov/xHgtg

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