Advanced Photon Source

Advanced Photon Source The Advanced Photon Source (APS) is a national synchrotron x-ray research facility at Argonne National Laboratory.

The APS provides the brightest x-ray beams in the Western Hemisphere to more than 5,000 scientists worldwide. The APS is one of the most technologically complex machines in the world. This premier national research facility provides ultra-bright, high-energy x-ray beams to more than 5,000 (and growing) scientists from around the United States and the world.

Science Friday! A hormone best known for regulating appetite may hold the key to treating fibrosis. Using X-ray crystall...
05/29/2026

Science Friday! A hormone best known for regulating appetite may hold the key to treating fibrosis. Using X-ray crystallography at the Advanced Photon Source, researchers developed an antibody that blocks leptin signaling and reduced fibrosis in the liver, kidney, lung, and blood vessels in mouse models. The work opens a promising new path toward therapies for organ scarring and failure.

https://www.aps.anl.gov/APS-Science-Highlight/2026-05-29/leptins-role-in-fibrosis-may-lead-to-the-development-of-new

Registration is now open for Argonne National Laboratory's first open house in three years.On June 27, visitors will hav...
05/27/2026

Registration is now open for Argonne National Laboratory's first open house in three years.

On June 27, visitors will have a rare opportunity to explore the world-class facilities, technologies, and research helping strengthen America’s future through scientific discovery and innovation.

From securing America’s energy future and accelerating science with AI to understanding our universe and creating the tools that make breakthrough discoveries possible, offers a behind-the-scenes look at research that supports U.S. competitiveness, security, and scientific leadership.

Space is limited! Go here to sign up: https://www.anl.gov/open-house/2026

Science Friday! Scientists used X-rays at the Advanced Photon Source to decode a long-unsolved vitamin B12 transport str...
05/22/2026

Science Friday! Scientists used X-rays at the Advanced Photon Source to decode a long-unsolved vitamin B12 transport structure, revealing a rare cobalt-sulfur “molecular clasp” that protects and precisely releases this essential nutrient. The discovery sheds light on how B12 trafficking fails in genetic disorders and could guide future treatments for vitamin B12 deficiency.

https://www.aps.anl.gov/APS-Science-Highlight/2026-05-21/an-unstable-bond-tethers-a-molecule-critical-for-life

05/21/2026

Throwback Thursday! Flash back with us to the mid-'90s as the Advanced Photon Source took shape. What you see here is the work of hundreds of dedicated people, and their legacy continues with the upgraded APS. The next user run begins next week!

Scientists have used X-ray interferometry to reveal hidden quantum order in a complex material—unlocking a new way to me...
05/19/2026

Scientists have used X-ray interferometry to reveal hidden quantum order in a complex material—unlocking a new way to measure the elusive phenomenon of quantum entanglement. By studying how scattered X-rays interfere inside a crystal, researchers reconstructed the material’s “entanglement spectrum,” exposing a previously invisible electronic phase that coexists with known magnetic order.

The breakthrough, achieved in part at the Advanced Photon Source, shows how powerful X-ray techniques can uncover the deeply entangled states that give rise to exotic quantum behaviors. The findings could help scientists better understand—and ultimately control—the quantum phases that underpin future technologies like quantum computing and advanced electronic materials.

https://www.aps.anl.gov/APS-Science-Highlight/2026-05-19/revealing-quantum-entanglement-and-hidden-order-in-real-materials

Today is the International Day of Light, when we celebrate the work of light sources such as the Advanced Photon Source ...
05/16/2026

Today is the International Day of Light, when we celebrate the work of light sources such as the Advanced Photon Source to illuminate the mysteries of our world. From improving the microelectronics in your phone to creating safer materials for nuclear reactors to laying the groundwork for new treatments against infectious diseases, photon sources shine a much-needed light into our lives, changing them for the better. Here at the APS, our users (some of whom you can see in the photos below, from our most recent user runs) bring us some of the most pressing challenges of our time and use our ultrabright X-ray beams to find solutions. It's an extraordinary thing to be a part of, today and every day.

Shout out to our sister light sources from around the world, and to Lightsources.org for bringing them together.

If you want to join the National X-ray School at the Advanced Photon Source this year, the clock is ticking. The deadlin...
05/13/2026

If you want to join the National X-ray School at the Advanced Photon Source this year, the clock is ticking. The deadline for registration is Friday.

Hosted by the APS at Argonne National Laboratory, this highly competitive program offers an intensive, hands-on introduction to X-ray characterization—combining expert-led lectures with hands-on experimental experience. Designed for early-career graduate students using X-ray methods in their research, this immersive program is a unique opportunity to build skills, expand your network, and accelerate your scientific impact

For more information: https://www.anl.gov/education/national-xray-school

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