Advanced Photon Source

Advanced Photon Source The Advanced Photon Source (APS) is a national synchrotron x-ray research facility at Argonne National Laboratory.

The APS provides the brightest x-ray beams in the Western Hemisphere to more than 5,000 scientists worldwide. The APS is one of the most technologically complex machines in the world. This premier national research facility provides ultra-bright, high-energy x-ray beams to more than 5,000 (and growing) scientists from around the United States and the world.

Science Friday! Researchers have discovered that a key material used to build advanced oxide electronics doesn’t grow qu...
09/04/2026

Science Friday! Researchers have discovered that a key material used to build advanced oxide electronics doesn’t grow quite the way scientists thought. Using molecular beam epitaxy and real-time synchrotron X-ray scattering at the Advanced Photon Source, they watched strontium titanate films grow atom by atom—and found that an extra layer of titanium dioxide reshuffles during growth, changing the structure of the material’s interface.

The finding could reshape how scientists design and build complex oxide materials, whose properties depend heavily on precisely controlled interfaces. It also shows why watching materials grow in real time with powerful X-ray tools can reveal hidden atomic-scale processes.

https://www.aps.anl.gov/APS-Science-Highlight/2026-09-04/atomic-layer-growth-on-a-key-substrate-is-more-complex-than-it

Throwback Thursday! As we ramp up for the next cycle of user science at the APS, here are some scenes from the previous ...
09/03/2026

Throwback Thursday! As we ramp up for the next cycle of user science at the APS, here are some scenes from the previous cycle. We brought the last two of our new feature beamlines, 3DMN and Atomic, online and brought in scientists to conduct first experiments on them. Below you'll see some images from those first experiments, including scientists from Penn State and Clemson University.

Stay tuned for the next chapter of science at the APS!

Researchers used Google DeepMind’s AlphaFold 3 to screen more than 900,000 compounds for new covalent inhibitors of the ...
09/01/2026

Researchers used Google DeepMind’s AlphaFold 3 to screen more than 900,000 compounds for new covalent inhibitors of the disease-related protein BTK. The AI identified three promising compounds, and X-ray crystallography at the Advanced Photon Source confirmed that two bound to BTK almost exactly as predicted—highlighting how AI and powerful X-ray tools could work together to accelerate drug discovery. Read more!

https://www.aps.anl.gov/APS-Science-Highlight/2026-09-01/using-ai-tools-to-enhance-virtual-screening-for-covalent-drug

We're a couple weeks away from the 14th International Conference on Inelastic X-ray Scattering, which we are hosting her...
08/31/2026

We're a couple weeks away from the 14th International Conference on Inelastic X-ray Scattering, which we are hosting here at the APS. Between Sept. 13 and Sept. 18 will be more than 50 talks on techniques and scientific results in the inelastic X-ray scattering realm. Learn more and register at the link!

https://bit.ly/4qMqIx3

Light can do more than make this lead-free perovskite glow—it can temporarily reshape the material itself. Using optical...
08/25/2026

Light can do more than make this lead-free perovskite glow—it can temporarily reshape the material itself. Using optical and time-resolved X-ray techniques at the Advanced Photon Source, researchers discovered a light-induced structural phase that lasts for milliseconds, revealing a new way these materials can store the effects of light. The finding could help advance lead-free materials for applications such as sensitive photodetectors.

https://www.aps.anl.gov/APS-Science-Highlight/2026-08-25/light-triggers-hidden-phase-transition-in-lead-free-perovskites

Science Friday! Researchers are designing new antibiotics to fight two drug-resistant “ESKAPE” pathogens, Klebsiella pne...
08/21/2026

Science Friday! Researchers are designing new antibiotics to fight two drug-resistant “ESKAPE” pathogens, Klebsiella pneumoniae and Acinetobacter baumannii. By modifying natural antibiotic compounds and using X-ray crystallography at the Advanced Photon Source to see how they bind to a key bacterial enzyme, the team identified promising candidates for further development.

https://www.aps.anl.gov/APS-Science-Highlight/2026-08-20/finding-new-inhibitors-that-target-the-eskape-pathogens

“Hearing that research at the APS had contributed to multiple Nobel Prizes was an incredible draw. By helping upgrade th...
08/18/2026

“Hearing that research at the APS had contributed to multiple Nobel Prizes was an incredible draw. By helping upgrade the storage ring, I would be facilitating the next scientific breakthroughs, and I wanted to have that impact.”

Meet Mechanical Engineer Heath Wayman, who helped to design the 1,321 magnets that make up the new APS storage ring, in the latest of our People of the APS series of profiles.

https://www.anl.gov/article/heath-waymans-field-designing-magnets-that-brighten-the-advanced-photon-source

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